Radiologic Evaluation of Compressive Osseointegration for the Fixation of Reconstruction Prostheses after Tumor Resection

Biomed Res Int. 2015:2015:513939. doi: 10.1155/2015/513939. Epub 2015 Jul 22.

Abstract

Objective: In pursuance of thoroughly understanding and facilitating the evaluation of the radiological changes in the preloaded bone by Compliant Pre-Stress osseointegration (Compress Biomet, Warsaw, Indiana) a new staging method was created depicting four stages.

Methods: Two cohorts (10 and 17 patients resp., not-receiving and receiving chemotherapy) were compared in terms of progression of osseointegration. Based on the changes at the bone-metal interface seen on röntgenorgrams four stages were defined: stage 0: immediate postoperative status, no ingrowth, or noncalcified callus; stage 1: early mineralization, calcified callus; stage 2: mature mineralization; and stage 3: hypertrophy at the level of the pins.

Results: There were no significant differences between the two cohorts. Group 2, which was significantly younger than group 1 (p < 0.001), presented a delayed initial rate of bone formation and reached stage 1 at 6 months instead of 3 months like group 1. The children from the group 2 demonstrated a visible rebound ingrowth.

Conclusion: Despite the fact that the staging fails to demonstrate a statistical difference, it is rather simple and can be used for future studies.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Bone Neoplasms / diagnostic imaging*
  • Bone Neoplasms / drug therapy
  • Bone Neoplasms / surgery*
  • Child
  • Demography
  • Female
  • Humans
  • Internal Fixators*
  • Male
  • Middle Aged
  • Osseointegration*
  • Osteogenesis
  • Prostheses and Implants*
  • Radiography
  • Young Adult