hERG potassium channel inhibition by ivabradine requires channel gating

J Mol Cell Cardiol. 2015 Oct:87:126-8. doi: 10.1016/j.yjmcc.2015.08.002. Epub 2015 Aug 11.

¹ School of Physiology & Pharmacology, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
² Department of Cardiovascular Sciences, Cardiology Group, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK.
³ Department of Cell Physiology and Pharmacology, Maurice Shock Medical Sciences Building, University Road, PO Box 138, Leicester LE1 9HN, UK.
⁴ School of Biochemistry, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
⁵ Department of Cardiovascular Sciences, Cardiology Group, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK; NIHR Leicester Cardiovascular Biomedical Research Unit, Leicester LE3 9QP, UK.
⁶ School of Physiology & Pharmacology, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK. Electronic address: jules.hancox@bristol.ac.uk.

No abstract available

Publication types

Animals
Benzazepines / pharmacology*
Ether-A-Go-Go Potassium Channels / antagonists & inhibitors*
Humans
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels / antagonists & inhibitors*
Myocytes, Cardiac / physiology*
Potassium Channel Blockers / pharmacology*