Monitoring therapeutic response of human superficial tumors using phase-encoded spectroscopy

Magn Reson Med. 1989 Dec;12(3):369-78. doi: 10.1002/mrm.1910120309.

Abstract

A one-dimensional phase-encoded spectroscopy sequence was implemented on a GE 1.5-T Signa imager and the feasibility of its application to monitor the 31P metabolites of superficial tumors was demonstrated. Serial 31P spectra of 1-cm slices with adequate signal-to-noise ratio and insignificant T2 weighting can be obtained in 28 min. The degree of "bleeding" effect was reduced with increased phase-encoding steps.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Models, Structural
  • Neoplasms / metabolism*
  • Neoplasms / therapy
  • Phosphorus

Substances

  • Phosphorus