Phosphatidylcholine's functions beyond that of a membrane brick

Mol Membr Biol. 2015;32(4):117-9. doi: 10.3109/09687688.2015.1066894. Epub 2015 Aug 25.

Abstract

Since its discovery in the 19th century, phosphatidylcholine (PC) has been regarded primarily as a structural lipid. However, more recent evidence, much of it in the last five years, strongly suggests that PC has other roles. Here, we explore some of that new evidence and consider the possibility that the ultimate role of phosphatidylcholine may not be predictable.

Keywords: Lipid isoforms; lipid signalling; phosphatidylcholine.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Membrane / chemistry
  • Cell Membrane / metabolism*
  • Gene Expression Regulation
  • Humans
  • Phosphatidylcholines / chemistry
  • Phosphatidylcholines / metabolism*
  • Protein Binding
  • Signal Transduction

Substances

  • Phosphatidylcholines