Does pregnancy-induced hypertension affect the electrophysiology of the heart?

J Obstet Gynaecol. 2016;36(2):183-6. doi: 10.3109/01443615.2015.1036401. Epub 2015 Sep 14.

Abstract

Pregnancy-induced hypertension (PIHT) increases both maternal and neonatal mortality and morbidity in pregnant women. We sought to investigate the electrocardiographic findings in pregnant women with PIHT. Seventeen pregnant women (29.4 ± 5 years) with PIHT and 24 pregnant women (27.3 ± 6.1 years) with normal blood pressure (control group) were included in the study. A 12-lead surface electrocardiogram was used to evaluate the electrocardiographic parameters. Pregnant women with PIHT had higher blood pressure (p = 0.001). The Tp-e interval was longer in PIHT pregnant women at 83.5 ± 7.8 ms versus 75.8 ± 8.4 ms in the control group (p = 0.007). The Tp-e/QTc ratio was higher in pregnant women with PIHT than that in healthy controls (0.19 ± 0.02 vs. 0.18 ± 0.02, respectively). This study demonstrated that Pd, QTd and the P wave durations were similar in the PIHT pregnant women and control group, but the Tp-e and Tp-e/QTc ratio were higher in pregnant women with PIHT than in normotensive pregnant women.

Keywords: P wave dispersion; Pregnancy-induced hypertension; QT dispersion; Tp-e interval; Tp-e/QT ratio.

MeSH terms

  • Adult
  • Blood Pressure
  • Case-Control Studies
  • Electrocardiography
  • Female
  • Heart / physiopathology*
  • Humans
  • Hypertension, Pregnancy-Induced / physiopathology*
  • Pregnancy
  • Young Adult