Metacognitive processes in psychometrically defined schizotypy

Psychiatry Res. 2015 Dec 15;230(2):279-86. doi: 10.1016/j.psychres.2015.09.006. Epub 2015 Sep 8.

Abstract

Metacognitive abnormalities have been implicated in the experience of psychotic symptoms; however, the process through which this occurs remains unclear. The aim of this study was to clarify the association of self-reported schizotypy with metacognitive beliefs and neural activity related to higher-order cognition. Event-related potentials (ERPs) including the error-related negativity (ERN) and error positivity (Pe) were recorded during a Flanker task in 20 controls and 22 individuals with high self-reported schizotypy on the Schizotypal Personality Questionnaire-Brief Revised (SPQ-BR). Participants continuously evaluated their task performance and completed the Metacognitions Questionnaire-30 (MCQ-30). The high schizotypy group demonstrated higher scores on all subscales of the MCQ-30. In contrast, task performance, accuracy of self-performance evaluation, and amplitudes of the ERN and Pe did not differ between groups. The MCQ-30 factors that measure cognitive confidence and positive beliefs about worry significantly predicted SPQ-BR total score, whereas ERPs did not. High self-reported schizotypy appears to be more associated with dysfunctional metacognitive beliefs than physiological abnormalities in brain areas related to metacognition.

Keywords: Error monitoring; Error-related negativity; Metacognitive beliefs; Psychosis; Schizotypy.

MeSH terms

  • Adolescent
  • Anxiety
  • Case-Control Studies
  • Electroencephalography
  • Evoked Potentials / physiology*
  • Female
  • Humans
  • Male
  • Metacognition*
  • Psychometrics
  • Psychotic Disorders / physiopathology
  • Psychotic Disorders / psychology*
  • Schizotypal Personality Disorder / physiopathology
  • Schizotypal Personality Disorder / psychology*
  • Surveys and Questionnaires
  • Task Performance and Analysis
  • Young Adult