Gelling process for sodium alginate: New technical approach by using calcium rich micro-spheres

Carbohydr Polym. 2015 Dec 10:134:767-74. doi: 10.1016/j.carbpol.2015.08.064. Epub 2015 Aug 22.

Abstract

Alginate based materials have become an important class of products in many fields from the pharmaceutical industry to tissue engineering, because of their ability to create stimuli responsive hydrogels. We present a new technical approach for obtaining a controlled gelling process, based on the quantities of Ca(2+) rich alginate micro-beads added as crosslinkers. The gels have been evaluated in light of the amount of Ca(2+) added to the alginate solution, and in light of the different dimensions of the micro-beads, using rheological measurements to assess the variation in the storage modulus (G'), loss modulus (G'') and complex viscosity (η(*)) as well as swelling and deswelling tests. The methodology was developed to obtain a material with specific characteristics for application in the field of conservation. The material had to be able to create a stable gel after being applied on the artwork surface and to confine the solvent action at the interface during cleaning operations.

Keywords: Alginate micro-spheres; Calcium chloride (PubChem CID: 5284359); Rheological properties; Sodium alginate; Sodium calcium alginate (PubChem CID: 6850754); Swelling test.

MeSH terms

  • Alginates / chemistry*
  • Calcium / chemistry*
  • Gels
  • Glucuronic Acid / chemistry
  • Hexuronic Acids / chemistry
  • Microspheres*
  • Rheology
  • Viscosity

Substances

  • Alginates
  • Gels
  • Hexuronic Acids
  • Glucuronic Acid
  • Calcium