The effect of gender on outcomes of aortoiliac artery interventions for claudication

Venkataramu N Krishnamurthy; Muhammad Naeem; Timothy P Murphy; Joselyn Cerezo; Paul Gaither Jordan; Suzanne H Goldberg; Abby G Ershow; Alan T Hirsch; Niki Oldenburg; Donald E Cutlip

doi:10.1016/j.clinimag.2015.09.003

The effect of gender on outcomes of aortoiliac artery interventions for claudication

Clin Imaging. 2016 Jan-Feb;40(1):96-100. doi: 10.1016/j.clinimag.2015.09.003. Epub 2015 Sep 4.

Authors

Affiliations

¹ Radiology Services, VA Ann Arbor Health System, 2215 Fuller Road, Mail Code 114, Ann Arbor, MI, USA. Electronic address: venkkris@umich.edu.
² Vascular Disease Research Center, Department of Diagnostic Imaging, Division of Vascular and Interventional Radiology, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI, USA. Electronic address: mnaeem@Lifespan.org.
³ Vascular Disease Research Center, Department of Diagnostic Imaging, Division of Vascular and Interventional Radiology, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI, USA. Electronic address: TMurphy@Lifespan.org.
⁴ Vascular Disease Research Center, Department of Diagnostic Imaging, Division of Vascular and Interventional Radiology, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI, USA. Electronic address: jvcerezo1@gmail.com.
⁵ Vascular Disease Research Center, Department of Diagnostic Imaging, Division of Vascular and Interventional Radiology, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI, USA. Electronic address: pjordan@Lifespan.org.
⁶ Nutrition Branch, Division of Cardiovascular Diseases, National Heart, Lung and Blood Institute, National Institute of Health, Bethesda, MD, USA.
⁷ Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, 6701 Rockledge Drive, Room 8160, MSC 7956, Bethesda, MD, USA. Electronic address: ErshowA@nhlbi.nih.gov.
⁸ Cardiovascular Division and Lillehei Heart Institute, University of Minnesota Medical School, 420 Delaware Street SE, MMC 508, Minneapolis, MN, USA. Electronic address: hirsc005@umn.edu.
⁹ Cardiovascular Division and Lillehei Heart Institute, University of Minnesota Medical School, 420 Delaware Street SE, MMC 508, Minneapolis, MN, USA. Electronic address: olden019@umn.edu.
¹⁰ Clinical Investigations, Harvard Clinical Research Institute, 930 Commonwealth Avenue, Boston, MA, USA. Electronic address: don.cutlip@hcri.harvard.edu.

Abstract

Objective: To explore the relationship between gender, native artery diameters, and outcomes of stent revascularization (ST) in the "Claudication: Exercise versus Endoluminal Revascularization" trial.

Methods: A comparative analysis was performed of the impact of gender, age, weight, height, body mass index, and body surface area on revascularization outcomes at baseline and 6months in 55 arterial segments of aorta, common iliac artery, and external iliac artery (EIA).

Results: Women demonstrated smaller diameter of the EIA. However, the clinical outcomes of revascularization were not negatively affected by the gender-based differences.

Conclusion: Gender-based differences are unlikely to significantly impact outcome of ST.

Keywords: Aortoiliac stent; Gender differences; Peripheral arterial disease; Vessel diameter.

Published by Elsevier Inc.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Aged
Aorta / surgery*
Constriction, Pathologic / surgery*
Female
Follow-Up Studies
Humans
Iliac Artery / surgery*
Intermittent Claudication / surgery*
Male
Middle Aged
Prospective Studies
Sex Factors
Stents*
Treatment Outcome

Abstract

Publication types

MeSH terms

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