[Oocyte vitrification: for whom?]

Ned Tijdschr Geneeskd. 2015:159:A9361.
[Article in Dutch]

Abstract

Objective: To study the indications of oocyte vitrification in women who undergo this intervention.

Design: Cross-sectional study.

Method: We collected the indications of oocyte vitrification in women who underwent, or started ovarian stimulation for, this intervention between May 2006 and December 31st 2013. Indications were subcategorized into six groups: no sperm available during IVF or ICSI treatment, planned gonadotoxic therapy, ovarian surgery, risk on premature ovarian insufficiency , previous gonadotoxic therapy, and anticipated gamete exhaustion.

Results: During the study period 298 women vitrified oocytes or started with ovarian stimulation for oocyte vitrification. The majority of the women (33%) vitrified oocytes because of anticipated gamete exhaustion. Planned gonadotoxic treatment was for 81 women (27%) the reason for oocyte vitrification.

Conclusion: With oocyte vitrification women are able to extend the time at which they can conceive. The future will tell whether the benefits of oocyte vitrification outweigh the risks and costs.

MeSH terms

  • Adult
  • Age Factors
  • Cost-Benefit Analysis
  • Cross-Sectional Studies
  • Cryopreservation / methods*
  • Female
  • Fertility / physiology*
  • Humans
  • Oocytes / growth & development*
  • Ovulation Induction
  • Risk Assessment
  • Vitrification