Relevant role of von Willebrand factor in neutrophil recruitment in a mouse sepsis model involving cecal ligation and puncture

Haematologica. 2016 Feb;101(2):e52-4. doi: 10.3324/haematol.2015.135434. Epub 2015 Oct 22.
No abstract available

Keywords: neutrophil recruitment; sepsis; von Willebrand factor.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
  • Cecum / drug effects
  • Cecum / microbiology
  • Cecum / pathology
  • Disease Models, Animal
  • Gene Deletion
  • Humans
  • Leukocyte Count
  • Ligation
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Neutrophil Infiltration / drug effects*
  • Neutrophils / drug effects*
  • Neutrophils / immunology
  • Peritoneal Cavity / microbiology
  • Peritoneal Cavity / pathology
  • Punctures
  • Sepsis / drug therapy*
  • Sepsis / microbiology
  • Sepsis / mortality
  • Sepsis / pathology
  • Survival Analysis
  • von Willebrand Factor / genetics
  • von Willebrand Factor / pharmacology*

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • von Willebrand Factor