Skeletal Muscle Microvasculature: A Highly Dynamic Lifeline

Claire Latroche; Cyril Gitiaux; Fabrice Chrétien; Isabelle Desguerre; Rémi Mounier; Bénédicte Chazaud

doi:10.1152/physiol.00026.2015

Skeletal Muscle Microvasculature: A Highly Dynamic Lifeline

Physiology (Bethesda). 2015 Nov;30(6):417-27. doi: 10.1152/physiol.00026.2015.

Authors

Claire Latroche¹, Cyril Gitiaux¹, Fabrice Chrétien², Isabelle Desguerre³, Rémi Mounier⁴, Bénédicte Chazaud⁵

Affiliations

¹ Institut Cochin, INSERM U1016, Paris, France; CNRS 8104, Paris, France; Université Paris Descartes, Paris, France; Institut Pasteur, Paris, France;
² Institut Pasteur, Paris, France;
³ Institut Cochin, INSERM U1016, Paris, France; CNRS 8104, Paris, France; Université Paris Descartes, Paris, France;
⁴ CGPhyMC, CNRS UMR5534, Villeurbanne, France; and Université Claude Bernard Lyon1, Villeurbanne, France.
⁵ Institut Cochin, INSERM U1016, Paris, France; CNRS 8104, Paris, France; Université Paris Descartes, Paris, France; CGPhyMC, CNRS UMR5534, Villeurbanne, France; and Université Claude Bernard Lyon1, Villeurbanne, France benedicte.chazaud@inserm.fr.

PMID: 26525341
DOI: 10.1152/physiol.00026.2015

Abstract

Skeletal muscle is highly irrigated by blood vessels. Beyond oxygen and nutrient supply, new vessel functions have been identified. This review presents vessel microanatomy and functions at tissue, cellular, and molecular levels. Mechanisms of vessel plasticity are described during skeletal muscle development and acute regeneration, and in physiological and pathological contexts.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Adaptation, Physiological
Animals
Endothelial Progenitor Cells / physiology
Humans
Microcirculation*
Microvessels / anatomy & histology
Microvessels / physiology*
Muscle Development
Muscle, Skeletal / blood supply*
Muscular Diseases / pathology
Muscular Diseases / physiopathology
Myoblasts, Skeletal / physiology
Neovascularization, Physiologic
Stem Cell Niche