How will new and future therapies change our treatment of IBD?

Expert Rev Clin Immunol. 2016;12(3):233-6. doi: 10.1586/1744666X.2016.1112271. Epub 2015 Nov 11.

Abstract

Fundamental insights into the pathogenesis of inflammatory bowel diseases (IBD) have led to the development of new therapies and lots of experimental compounds in the pipeline. Our treatment of IBD is therefore constantly evolving. In this editorial, we postulate that bi- or even polyspecific therapy will be an important mainstay of future IBD treatment. Moreover, we highlight some promising new therapeutic concepts currently under investigation and point at the outstanding and growing importance of personalized medicine to assign drugs from the increasing pool of options to the individual patient.

Keywords: cytokines; gut homing; immunology; inflammatory bowel diseases; personalized medicine.

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Monoclonal / therapeutic use*
  • Combined Modality Therapy
  • Cytokines / immunology
  • Humans
  • Immunotherapy / methods*
  • Inflammatory Bowel Diseases / immunology
  • Inflammatory Bowel Diseases / therapy*
  • Precision Medicine

Substances

  • Antibodies, Monoclonal
  • Cytokines