Locally advanced basal cell carcinoma has a distinct methylation and transcriptomic profile

Exp Dermatol. 2016 Apr;25(4):316-8. doi: 10.1111/exd.12905. Epub 2016 Feb 11.

Tjinta Brinkhuizen^{1

2}, Michel van Geel^{1

2

3}, Simon L I J Denil^{4

5}, Tim De Meyer⁴, Nicole W J Kelleners-Smeets^{1

2}, Peter J F M Lohuis⁶, Frank J P Hoebers^{2

7}, Véronique J L Winnepenninckx^{2

8}, Maurice A M van Steensel^{1

2

3

5

9}, Klara Mosterd^{1

2}

¹ Department of Dermatology, Maastricht University Medical Centre, Maastricht, The Netherlands.
² GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
³ Department of Clinical Genetics, Maastricht University Medical Centre, Maastricht, The Netherlands.
⁴ Department of Mathematical Modelling Statistics and Bioinformatics, Ghent University, Ghent, Belgium.
⁵ Institute of Medical Biology Immunos, Singapore, Singapore.
⁶ Netherlands Cancer Institute/ Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
⁷ Department of Radiation Oncology (Maastro), Maastricht University Medical Centre, Maastricht, The Netherlands.
⁸ Department of Pathology, Maastricht University Medical Centre, Maastricht, The Netherlands.
⁹ Cancer Research Division School of Medicine Dentistry and Nursing, Division of Biological Chemistry and Drug Development College of Life Sciences, University of Dundee, Dundee, UK.

No abstract available

Keywords: MMP13; epigenetics; locally advanced basal cell carcinoma; methylome; transciptomics.

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