Effect of supplemental oxygen 80 % on post-tonsillectomy nausea and vomiting: a randomized controlled trial

Eur Arch Otorhinolaryngol. 2016 May;273(5):1215-9. doi: 10.1007/s00405-015-3858-4. Epub 2015 Dec 18.

Abstract

Nausea and vomiting are two of the most common complications of tonsillectomy in children. Administration of supplemental 80 % oxygen during surgery reduces the incidence of postoperative nausea and vomiting. We aimed to test the efficacy of supplemental 80 % oxygen during tonsillectomy on postoperative nausea and vomiting. In a randomized controlled trial in Shahid Mostafa Khomeini Hospital in Tehran, 102 children scheduled for tonsillectomy (± adenoidectomy) under general anesthesia were divided randomly in two groups according to percent of administered oxygen (group 1:30 % oxygen, group 2:80 % oxygen). The incidence of postoperative nausea and vomiting were assessed and compared in 0-2, 2-6 and 6-24 h after surgery. Incidence of post-tonsillectomy nausea and vomiting after 2, 2-6, and 6-24 h was 13.72, 1.96 and 1.96 % for group 1 and 3.92, 0 and 1.96 % in group 2, respectively. We found no statistically significant difference between two groups (P = 0.08) but 80 % oxygen was beneficial for reducing postoperative nausea and vomiting in the first 2 h after surgery in group 2.

Keywords: Nausea; Supplemental oxygen; Tonsillectomy; Vomiting.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adenoidectomy / adverse effects
  • Adolescent
  • Anesthesia, General
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Incidence
  • Iran
  • Male
  • Oxygen Inhalation Therapy / methods*
  • Postoperative Nausea and Vomiting / epidemiology
  • Postoperative Nausea and Vomiting / prevention & control*
  • Tonsillectomy / adverse effects*