Decline in Decreased Cephalosporin Susceptibility and Increase in Azithromycin Resistance in Neisseria gonorrhoeae, Canada

Emerg Infect Dis. 2016 Jan;22(1):65-7. doi: 10.3201/eid2201.151247.

Abstract

Antimicrobial resistance profiles were determined for Neisseria gonorrhoeae strains isolated in Canada during 2010-2014. The proportion of isolates with decreased susceptibility to cephalosporins declined significantly between 2011 and 2014, whereas azithromycin resistance increased significantly during that period. Continued surveillance of antimicrobial drug susceptibilities is imperative to inform treatment guidelines.

Keywords: Canada; Neisseria gonorrhoeae; antimicrobial resistance; azithromycin; bacteria; cephalosporins; gonorrhea; gonorrhoea; rates; susceptibility.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Azithromycin / therapeutic use*
  • Canada
  • Cephalosporins / therapeutic use*
  • Drug Resistance, Bacterial / drug effects*
  • Gonorrhea / drug therapy*
  • Humans
  • Microbial Sensitivity Tests / methods
  • Neisseria gonorrhoeae / drug effects*

Substances

  • Anti-Bacterial Agents
  • Cephalosporins
  • Azithromycin