Randomized double-blind evaluation of ciprofloxacin and doxycycline for Mediterranean spotted fever

F Gudiol; R Pallares; J Carratala; F Bolao; J Ariza; G Rufi; P F Viladrich

doi:10.1128/AAC.33.6.987

Randomized double-blind evaluation of ciprofloxacin and doxycycline for Mediterranean spotted fever

Antimicrob Agents Chemother. 1989 Jun;33(6):987-8. doi: 10.1128/AAC.33.6.987.

Authors

F Gudiol¹, R Pallares, J Carratala, F Bolao, J Ariza, G Rufi, P F Viladrich

Affiliation

¹ Department of Medicine, Bellvitge Hospital, University of Barcelona, Spain.

Abstract

A study of 43 patients with Mediterranean spotted fever showed that a 2-day course of ciprofloxacin or a 2-day course of doxycycline may be an effective mode of therapy. All patients in both arms of the study were cured; however, doxycycline produced a more rapid defervescence.

Publication types

Clinical Trial
Randomized Controlled Trial

MeSH terms

Adult
Ciprofloxacin / therapeutic use*
Clinical Trials as Topic
Double-Blind Method
Doxycycline / therapeutic use*
Female
Humans
In Vitro Techniques
Male
Middle Aged
Random Allocation
Rickettsia Infections / drug therapy*

Substances

Ciprofloxacin
Doxycycline