Cannabinoid hyperemesis syndrome: a guide for the practising clinician

BMJ Case Rep. 2015 Dec 23:2015:bcr2015210246. doi: 10.1136/bcr-2015-210246.

Abstract

Cannabis is the most widely used illicit drug in the world. The medicinal value of cannabis as an antiemetic is well known by the medical fraternity. A less well-recognised entity is the potential for certain chronic users to develop hyperemesis. We describe the case of a young man who presented to us with features of cannabinoid hyperemesis syndrome. We review the current literature on this condition, its pathogenesis and management.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Antiemetics* / adverse effects
  • Antiemetics* / therapeutic use
  • Cannabinoids / adverse effects*
  • Cannabis / adverse effects
  • Cannabis / chemistry*
  • Disease Management*
  • Dronabinol / adverse effects
  • Humans
  • Male
  • Marijuana Abuse / complications*
  • Metoclopramide / therapeutic use
  • Nausea / etiology*
  • Nausea / metabolism
  • Nausea / therapy
  • Receptors, Cannabinoid / metabolism
  • Syndrome
  • Vomiting / etiology*
  • Vomiting / metabolism
  • Vomiting / therapy
  • Young Adult

Substances

  • Antiemetics
  • Cannabinoids
  • Receptors, Cannabinoid
  • Dronabinol
  • Metoclopramide