Clinical and Virologic Characteristics May Aid Distinction of Acute Adenovirus Disease from Kawasaki Disease with Incidental Adenovirus Detection

J Pediatr. 2016 Mar:170:325-30. doi: 10.1016/j.jpeds.2015.11.021. Epub 2015 Dec 18.

Abstract

Incidental adenovirus detection in Kawasaki disease (KD) is important to differentiate from acute adenovirus disease. Twenty-four of 25 children with adenovirus disease and mimicking features of KD had <4 KD-like features, predominance of species B or E, and higher viral burden compared with those with KD and incidental adenovirus detection.

Publication types

  • Comparative Study

MeSH terms

  • Acute Disease
  • Adenoviridae / isolation & purification*
  • Adenovirus Infections, Human / diagnosis*
  • Adenovirus Infections, Human / virology
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Female
  • Follow-Up Studies
  • Humans
  • Incidental Findings
  • Infant
  • Male
  • Mucocutaneous Lymph Node Syndrome / diagnosis*
  • Mucocutaneous Lymph Node Syndrome / virology
  • Retrospective Studies
  • Viral Load