Crohn's Disease treated with azathioprine and basal cell carcinoma : three cases and literature review

Acta Gastroenterol Belg. 2015 Dec;78(4):436-8.

Abstract

Three cases of basal cell carcinoma in Crohn's disease patients treated with azathioprine are described. A review of the literature is conducted concerning this association between the occurrence of basal cell carcinoma and the use of azathioprine. Recently, practical advice on screening and follow-up of these situations have been proposed but there are no validated dermatological recommendations.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Azathioprine / therapeutic use*
  • Carcinoma, Basal Cell / etiology
  • Carcinoma, Basal Cell / pathology*
  • Crohn Disease / complications
  • Crohn Disease / drug therapy*
  • Crohn Disease / pathology
  • Female
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Male
  • Middle Aged
  • Skin Neoplasms / etiology
  • Skin Neoplasms / pathology*

Substances

  • Immunosuppressive Agents
  • Azathioprine