Proptosis, Micrognathia, Low Set Ear and Chest Deformity in a Patient with Extra Marker Chromosome 22

Acta Med Iran. 2015 Dec;53(12):782-4.

Abstract

There is a number of syndromes, associated with proptosis, micrognathia, low-set ear and chest deformity. Herein, we report a 9-year-old female with such phenotype who was presented with a vaginal neuroma. The result of karyotype showed 47XX, with extra marker chromosome 22. Although such a manifestation had not been reported in the literature, it should be considered as a very rare manifestation of the disease.

Keywords: Cat eye syndrome; Congenital heart defects; Ocular coloboma; Vaginal neuroma..

Publication types

  • Case Reports

MeSH terms

  • Child
  • Chromosomes, Human, Pair 22 / genetics*
  • Coloboma / diagnosis
  • Coloboma / genetics
  • Ear / abnormalities
  • Exophthalmos / diagnosis*
  • Exophthalmos / genetics
  • Female
  • Humans
  • Karyotyping
  • Micrognathism / diagnosis*
  • Micrognathism / genetics
  • Phenotype
  • Syndrome