Actin polymerisation after FCγR stimulation of human fibroblasts is BCL10 independent

Clin Immunol. 2016 Feb:163:120-2. doi: 10.1016/j.clim.2016.01.003. Epub 2016 Jan 14.

Abstract

B-cell lymphoma 10 (BCL10) is not essential for actin polymerisation after FcγR stimulation in human fibroblasts.

Keywords: Actin polymerisation; BCL10; CBM complex; Combined immunodeficiency; FCγR; Primary immunodeficiency.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actins / metabolism*
  • Adaptor Proteins, Signal Transducing / genetics*
  • Adaptor Proteins, Signal Transducing / immunology
  • B-Cell CLL-Lymphoma 10 Protein
  • CARD Signaling Adaptor Proteins / immunology
  • Case-Control Studies
  • Caspases / immunology
  • Fibroblasts / immunology
  • Fibroblasts / metabolism*
  • Humans
  • Immunologic Deficiency Syndromes / genetics*
  • Immunologic Deficiency Syndromes / immunology
  • Immunologic Deficiency Syndromes / metabolism
  • Microscopy, Fluorescence
  • Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
  • NF-kappa B / immunology
  • Neoplasm Proteins / immunology
  • Polymerization*
  • Receptors, IgG / immunology*
  • Signal Transduction / immunology

Substances

  • Actins
  • Adaptor Proteins, Signal Transducing
  • B-Cell CLL-Lymphoma 10 Protein
  • BCL10 protein, human
  • CARD Signaling Adaptor Proteins
  • NF-kappa B
  • Neoplasm Proteins
  • Receptors, IgG
  • Caspases
  • MALT1 protein, human
  • Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein