Thrombotic complications following the administration of high-dose prothrombin complex concentrate for acute warfarin reversal

Am J Emerg Med. 2016 Aug;34(8):1736.e1-3. doi: 10.1016/j.ajem.2015.12.069. Epub 2015 Dec 28.

Authors

Wesley R Zemrak¹, Erin Kelley², Nicole L Kovacic², Deirdre M Mooney³, Jane G Morris⁴, Casey Z MacVane⁵, Jeffrey A Rosenblatt³

Affiliations

¹ Department of Pharmacy, Maine Medical Center, 22 Bramhall St, Portland, ME, 04102, United States. Electronic address: zemraw@mmc.org.
² Department of Pharmacy, Maine Medical Center, 22 Bramhall St, Portland, ME, 04102, United States.
³ Department of Cardiac Services, Maine Medical Center, 22 Bramhall St, Portland, ME, 04102, United States.
⁴ Department of Neurology, Maine Medical Center, 22 Bramhall St, Portland, ME, 04102, United States.
⁵ Department of Emergency Medicine, Maine Medical Center, 22 Bramhall St, Portland, ME, 04102, United States.

PMID: 26806175
DOI: 10.1016/j.ajem.2015.12.069

No abstract available

Publication types

Case Reports

MeSH terms

Aged, 80 and over
Anticoagulants / adverse effects*
Blood Coagulation Factors / adverse effects*
Blood Coagulation Factors / therapeutic use
Coronary Thrombosis / chemically induced
Coronary Thrombosis / diagnosis
Female
Femoral Vein
Gastrointestinal Hemorrhage / chemically induced
Gastrointestinal Hemorrhage / drug therapy*
Hemostatics / adverse effects*
Hemostatics / therapeutic use
Humans
Male
Middle Aged
Stroke / chemically induced*
Stroke / diagnosis
Thrombosis / chemically induced*
Thrombosis / diagnosis
Venous Thrombosis / chemically induced
Venous Thrombosis / diagnosis
Warfarin / adverse effects*

Substances

Anticoagulants
Blood Coagulation Factors
Hemostatics
prothrombin complex concentrates
Warfarin