Listeria meningoencephalitis and anti-GQ1b antibody syndrome

A Vergori; G Masi; D Donati; F Ginanneschi; P Annunziata; A Cerase; M Mencarelli; B Rossetti; A De Luca; G Zanelli

doi:10.1007/s15010-015-0862-y

Listeria meningoencephalitis and anti-GQ1b antibody syndrome

Infection. 2016 Aug;44(4):543-6. doi: 10.1007/s15010-015-0862-y. Epub 2016 Jan 29.

Authors

A Vergori¹, G Masi², D Donati², F Ginanneschi², P Annunziata², A Cerase³, M Mencarelli¹, B Rossetti¹, A De Luca¹, G Zanelli⁴

Affiliations

¹ University Division of Infectious Diseases, Department of Medical Biotechnologies, University of Siena, 53100, Siena, Italy.
² Department of Medicine, Surgery and Neurosciences, Clinical Neuroimmunology Unit, University of Siena, Siena, Italy.
³ Unit of Neuroimaging and Neurointervention, University Hospital of Siena, Siena, Italy.
⁴ University Division of Infectious Diseases, Department of Medical Biotechnologies, University of Siena, 53100, Siena, Italy. giacomo.zanelli1971@gmail.com.

PMID: 26825308
DOI: 10.1007/s15010-015-0862-y

Abstract

We report the first case of Listeria monocytogenes meningoencephalitis associated with anti-GQ1b antibody syndrome in an immunocompetent adult. A prompt diagnosis, made thanks to the multidisciplinary contribution, allowed a combined therapeutic approach leading to final favourable outcome, despite several intercurrent complications.

Keywords: Anti-GQ1b IgG antibody; Bickerstaff brainstem encephalitis; Listeria; Meningoencephalitis; Miller-Fisher syndrome.

Publication types

Case Reports

MeSH terms

Autoantibodies
Autoimmune Diseases*
Encephalitis*
Gangliosides / immunology*
Humans
Male
Meningitis, Listeria*
Middle Aged
Miller Fisher Syndrome

Substances

Autoantibodies
Gangliosides
GQ1b ganglioside