Radiation Toxicity to the Cardiovascular System

Curr Oncol Rep. 2016 Mar;18(3):15. doi: 10.1007/s11912-016-0502-4.

Abstract

Radiation therapy is an important component of cancer treatment, and today, it is applied to approximately 50% of malignancies, including valvular, myocardial, pericardial, coronary or peripheral vascular disease, and arrhythmias. An increased clinical suspicion and knowledge of those mechanisms is important to initiate appropriate screening for the optimal diagnosis and treatment. As the number of cancer survivors has been steadily increasing over the last decades, cardio-oncology, an evolving subspecialty of cardiology, will soon play a pivotal role in raising awareness of the increased cardiovascular risk and formulate strategies to optimally manage patients in this unique population.

Keywords: Radiation-induced cardiovascular toxicity; Valvular pericardial heart disease.

Publication types

  • Review

MeSH terms

  • Breast Neoplasms / radiotherapy
  • Cardiovascular Diseases / etiology*
  • Cardiovascular System / radiation effects*
  • Female
  • Head and Neck Neoplasms / radiotherapy
  • Humans
  • Neoplasms / mortality
  • Neoplasms / radiotherapy*
  • Radiation Injuries / etiology*
  • Radiotherapy / adverse effects*
  • Survivors