Stool bacterial load in preterm infants with necrotising enterocolitis

Bashir Abdulkadir; Andrew Nelson; Tom Skeath; Emma C L Marrs; John D Perry; Stephen P Cummings; Nicholas D Embleton; Janet E Berrington; Christopher J Stewart

doi:10.1016/j.earlhumdev.2016.01.018

Stool bacterial load in preterm infants with necrotising enterocolitis

Early Hum Dev. 2016 Apr:95:1-2. doi: 10.1016/j.earlhumdev.2016.01.018. Epub 2016 Feb 16.

Authors

Bashir Abdulkadir¹, Andrew Nelson¹, Tom Skeath², Emma C L Marrs³, John D Perry³, Stephen P Cummings⁴, Nicholas D Embleton², Janet E Berrington², Christopher J Stewart¹

Affiliations

¹ Faculty of Health and Life Sciences, Ellison Building, Northumbria University, Newcastle upon Tyne NE1 8ST, United Kingdom.
² Newcastle Neonatal Service, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom.
³ Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, United Kingdom.
⁴ Faculty of Health and Life Sciences, Ellison Building, Northumbria University, Newcastle upon Tyne NE1 8ST, United Kingdom. Electronic address: stephen.cummings@northumbria.ac.uk.

PMID: 26895407
DOI: 10.1016/j.earlhumdev.2016.01.018

Abstract

Resected gut tissue in necrotising enterocolitis (NEC) has a higher bacterial load than controls. Quantitative PCR was performed on longitudinal NEC and control stool samples (n=72). No significant difference in the total bacterial load was found between samples at diagnosis compared to controls or temporally within NEC.

Keywords: Gut microbiome; Necrotising enterocolitis; Preterm infant; qPCR.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacterial Load
Case-Control Studies
Enterocolitis, Necrotizing / microbiology*
Feces / microbiology*
Humans
Infant, Newborn
Infant, Premature*
Microbiota