Objective: Multidisciplinary discussion is essential in establishing the diagnosis of idiopathic pulmonary fibrosis (IPF) and in determining prognosis.
Conclusion: The CT and histopathologic correlate for IPF is usual interstitial pneumonitis (UIP). If a high-confidence diagnosis of UIP is made on CT, IPF is almost always the diagnosis, obviating lung biopsy. If a confident diagnosis of UIP cannot be made on CT, further assessment with lung biopsy and multidisciplinary discussion are often necessary to achieve a confident final diagnosis.
Keywords: CT; atypical usual interstitial pneumonitis; idiopathic pulmonary fibrosis (IPF); multidisciplinary discussion; usual interstitial pneumonitis (UIP).