Human Naive Embryonic Stem Cells: How Full Is the Glass?

Yixuan Wang; Shaorong Gao

doi:10.1016/j.stem.2016.02.012

Human Naive Embryonic Stem Cells: How Full Is the Glass?

Cell Stem Cell. 2016 Mar 3;18(3):301-3. doi: 10.1016/j.stem.2016.02.012.

Authors

Yixuan Wang¹, Shaorong Gao²

Affiliations

¹ Clinical and Translational Research Center of Shanghai First Maternity & Infant Hospital, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
² Clinical and Translational Research Center of Shanghai First Maternity & Infant Hospital, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China. Electronic address: gaoshaorong@tongji.edu.cn.

PMID: 26942847
DOI: 10.1016/j.stem.2016.02.012

Abstract

Human naive embryonic stem cells in the ground state of pluripotency provide a new opportunity to study human developmental biology and potential clinical applications. Two studies now report related work in human naive stem cell derivation and DNA methylation analysis, with one reporting some differences from oocyte and blastocyst profiles.