Post-stroke depression among stroke survivors attending two hospitals in Kampala Uganda

Afr Health Sci. 2015 Dec;15(4):1220-31. doi: 10.4314/ahs.v15i4.22.

Abstract

Background: The burden of stroke worldwide is increasing rapidly. There is paucity of data on post-stroke depression (PSD) among stroke survivors in Uganda, despite the high prevalence of PSD reported elsewhere.

Methods: In a cross-sectional study, we assessed adult participants with confirmed first stroke with a standardized questionnaire. The Patient Health Questionnaire-9 was used to assess for depression among non-aphasic patients while the Aphasic Depression Rating Scale was administered to aphasic patients. Univariable and multivariable analyses performed to describe associations with PSD.

Results: Forty three females (58.9%) and 30 males (41.1%) who had a stroke participated. Fifty eight (79.5%) had ischemic strokes and 12 participants (16.4%) were aphasic. The prevalence of PSD among the study participants was 31.5%. PSD was higher among patients assessed within 6 months after the onset of stroke. PSD was strongly associated with the total Barthel index of activities of daily living (BIADL) score; p=0.001. There was no significant association between demographic characteristics and PSD.

Conclusion: There is a high prevalence of unrecognized post-stroke depression. Post-stroke depression was strongly associated with the patient's inability to undertake activities of daily life. There is urgent need for integration of screening for and management of post-stroke depression among stroke survivors.

Keywords: Stroke; post-stroke depression.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Activities of Daily Living
  • Adult
  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Depression / epidemiology
  • Depression / etiology*
  • Depression / physiopathology
  • Depression / psychology*
  • Female
  • Hospitals, Urban
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Psychiatric Status Rating Scales
  • Risk Factors
  • Severity of Illness Index
  • Stroke / complications
  • Stroke / diagnosis
  • Stroke / epidemiology*
  • Stroke / psychology*
  • Surveys and Questionnaires
  • Survivors / psychology*
  • Survivors / statistics & numerical data*
  • Uganda / epidemiology
  • Urban Population