Cancer Immunosurveillance Caught in the Act

Pedro Berraondo; Alvaro Teijeira; Ignacio Melero

doi:10.1016/j.immuni.2016.03.004

Cancer Immunosurveillance Caught in the Act

Immunity. 2016 Mar 15;44(3):525-526. doi: 10.1016/j.immuni.2016.03.004.

Authors

Pedro Berraondo¹, Alvaro Teijeira¹, Ignacio Melero²

Affiliations

¹ Program of Immunology and Immunotherapy, Center for Applied Medical Research (CIMA), Clinica Universidad de Navarra and Navarra Institute for Health Research (IdiSNA), Pamplona, Navarra 31008, Spain.
² Program of Immunology and Immunotherapy, Center for Applied Medical Research (CIMA), Clinica Universidad de Navarra and Navarra Institute for Health Research (IdiSNA), Pamplona, Navarra 31008, Spain. Electronic address: imelero@unav.es.

PMID: 26982362
DOI: 10.1016/j.immuni.2016.03.004

Abstract

The role of the immune system in the control of cancer formation and progression has been a matter of considerable debate over many years. In this issue of Immunity, Mlecnik et al. (2016) show the importance of immunosurveillance in controlling tumors in a series of microsatellite-instable human colon carcinomas.

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MeSH terms

Colorectal Neoplasms / diagnosis*
Female
Humans
Immunoassay / methods*
Male
Pathology, Molecular / methods*
T-Lymphocyte Subsets / immunology*
Th1 Cells / immunology*