HIV/HCV Co-infection: Overcoming Barriers to Treatment

J Assoc Nurses AIDS Care. 2016 Jul-Aug;27(4):524-9. doi: 10.1016/j.jana.2016.02.009. Epub 2016 Feb 20.

Abstract

A critical step in the eradication of hepatitis C virus (HCV) infection is access to effective therapy. With the advent of interferon-free regimens, HCV providers and patients gained hope that the success seen in clinical trials could be translated to the real world. However, the exorbitant cost of the new direct-acting antivirals limits access to these medications to the general HCV population, especially underserved patients with public insurance. We used a descriptive qualitative approach to detail the measures necessary and challenges faced by an inner-city nursing team in Washington, DC to obtain the new direct-acting antivirals. Significant time and dedication on the part of providers and staff was required to assist patients with the process of obtaining direct-acting antivirals.

Keywords: HCV; HIV; direct-acting antivirals; managed care organizations; sustained virologic response; underserved population.

MeSH terms

  • Antiviral Agents / economics*
  • Antiviral Agents / supply & distribution
  • Antiviral Agents / therapeutic use*
  • Coinfection*
  • District of Columbia
  • Drug Costs*
  • HIV Infections / drug therapy*
  • Hepatitis C, Chronic / drug therapy*
  • Hepatitis C, Chronic / economics
  • Humans
  • Managed Care Programs
  • Simeprevir / economics
  • Simeprevir / supply & distribution
  • Simeprevir / therapeutic use
  • Sofosbuvir / economics
  • Sofosbuvir / supply & distribution
  • Sofosbuvir / therapeutic use
  • Vulnerable Populations*

Substances

  • Antiviral Agents
  • Simeprevir
  • Sofosbuvir