Generation of the Fip1l1-Pdgfra fusion gene using CRISPR/Cas genome editing

Leukemia. 2016 Sep;30(9):1913-6. doi: 10.1038/leu.2016.62. Epub 2016 Mar 8.

Authors

M Vanden Bempt^{1

2}, S Demeyer^{1

2}, N Mentens^{1

2}, E Geerdens^{1

2}, C E De Bock^{1

2}, I Wlodarska¹, J Cools^{1

2}

Affiliations

¹ KU Leuven Center for Human Genetics, Leuven, Belgium.
² VIB Center for the Biology of Disease, Leuven, Belgium.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

CRISPR-Cas Systems*
Gene Editing / methods*
Humans
Oncogene Proteins, Fusion / genetics*
Receptor, Platelet-Derived Growth Factor alpha / genetics*
mRNA Cleavage and Polyadenylation Factors / genetics*

Substances

Oncogene Proteins, Fusion
mRNA Cleavage and Polyadenylation Factors
FIP1L1-PDGFRA fusion protein, human
Receptor, Platelet-Derived Growth Factor alpha