Safety of prothrombin complex concentrate in healthy subjects

Br J Haematol. 2017 Feb;176(4):664-666. doi: 10.1111/bjh.13974. Epub 2016 Mar 30.

Authors

Stefano Barco^{1

2}, Chiara Picchi³, Alice Trinchero¹, Saskia Middeldorp², Michiel Coppens²

Affiliations

¹ Centre for Thrombosis and Haemostasis, University Medical Centre of the Johannes Gutenberg University, Mainz, Germany.
² Department of Vascular Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
³ Oncology Unit, Istituto di Cura Città di Pavia, Gruppo San Donato, University and Research Hospital, Pavia, Italy.

PMID: 27027385
DOI: 10.1111/bjh.13974

No abstract available

Keywords: anticoagulants; bleeding disorders; meta-analysis; prothrombin complex concentrate; reversal; thrombosis.

Publication types

Letter
Meta-Analysis

MeSH terms

Blood Coagulation / drug effects*
Blood Coagulation Factors / administration & dosage
Blood Coagulation Factors / adverse effects*
Healthy Volunteers
Hemorrhage / drug therapy
Hemorrhage / etiology
Humans

Substances

Blood Coagulation Factors
prothrombin complex concentrates