Insights into 6q21-q22: Refinement of the critical region for acro-cardio-facial syndrome

Congenit Anom (Kyoto). 2016 Jul;56(4):187-189. doi: 10.1111/cga.12164.

Abstract

Deletions on chromosome 6q are rarely reported in the literature, and genotype-phenotype correlations are poorly understood. We report a child with a deletion of the 6q21-q22 chromosomal region, providing some intriguing results about the correlation between this region and acro-cardio-facial syndrome, congenital heart disease, split hand and foot malformation, and epilepsy.

Keywords: 6q21-q22 deletion; NUS1; acro-cardio-facial syndrome; chromosome 6; epilepsy.

Publication types

  • Case Reports