Emerging infections due to filamentous fungi in humans and animals: only the tip of the iceberg?

Environ Microbiol Rep. 2016 Jun;8(3):332-42. doi: 10.1111/1758-2229.12404. Epub 2016 May 15.

Abstract

Over the last few decades, the number of patients susceptible to invasive filamentous fungal infections has steadily increased, especially in populations suffering from hematological diseases. The pathogens responsible for such mycoses are now quite well characterized, such as Aspergillus spp. - the most commonly isolated mold -, Mucorales, Fusarium spp., Scedosporium spp. or melanized fungi. An increase in the incidence of this category of 'emerging' fungi has been recently highlighted, evoking a shift in fungal ecology. Starting from these medical findings, taking a step back and adopt a wider perspective offers possible explanations of this phenomenon on an even larger scale than previously reported. In this review, we illustrate the link between emerging fungi in medicine and changes in ecology or human behaviours, and we encourage integrative approaches to apprehend the adverse effects of progress and develop preventive measures in vast domains, such as agriculture or medicine.

Publication types

  • Review

MeSH terms

  • Animals
  • Communicable Diseases, Emerging / epidemiology*
  • Communicable Diseases, Emerging / microbiology
  • Communicable Diseases, Emerging / veterinary*
  • Fungi / classification*
  • Fungi / isolation & purification*
  • Humans
  • Incidence
  • Mycoses / epidemiology*
  • Mycoses / microbiology
  • Mycoses / veterinary*