High prevalence and allele burden-independent prognostic importance of p53 mutations in an inner-city MDS/AML cohort

Leukemia. 2016 Aug;30(8):1793-5. doi: 10.1038/leu.2016.74. Epub 2016 Apr 29.

Authors

S Goel¹, J Hall², K Pradhan¹, C Hirsch³, B Przychodzen³, A Shastri¹, I Mantzaris¹, M Janakiram¹, R Battini¹, N Kornblum¹, O Derman¹, K Gritsman¹, J Al-Hafidh², Y Wang⁴, B Halmos¹, U Steidl¹, J P Maciejewski³, I Braunschweig¹, A Verma¹

Affiliations

¹ Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
² Genoptix, Carlsbad, CA, USA.
³ Taussig Cancer Center, Cleveland Clinic, Cleveland, OH, USA.
⁴ Department of Pathology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.

PMID: 27125205
DOI: 10.1038/leu.2016.74

No abstract available

Publication types

Letter

MeSH terms

Alleles
Cohort Studies
DNA Mutational Analysis
Humans
Leukemia, Myeloid, Acute / genetics*
Mutation
Myelodysplastic Syndromes / genetics*
Prevalence
Prognosis
Tumor Suppressor Protein p53 / genetics*
Urban Population

Substances

TP53 protein, human
Tumor Suppressor Protein p53