A fatal case of pulmonary infection by Mycobacterium colombiense in Para State, Amazon Region, Brazil

Diagn Microbiol Infect Dis. 2016 Jul;85(3):344-346. doi: 10.1016/j.diagmicrobio.2016.02.011. Epub 2016 Feb 9.

Abstract

Mycobacterium avium complex (MAC) is a heterogeneous group of species found in several environmental sources and that exhibit variable degrees of pathogenicity. Among the MAC members, Mycobacterium colombiense has been related to pulmonary disease and disseminated infection in HIV-infected patients in Colombia. Lymphadenopathy cases have also been reported. We have described a fatal case of M. colombiense pulmonary disease in a Brazilian patient without evidence of HIV infection or other known causes of immunosuppression.

Keywords: Fatal case; Mycobacterium colombiense; Pulmonary disease.

Publication types

  • Case Reports

MeSH terms

  • Antitubercular Agents / pharmacology
  • Brazil
  • Cluster Analysis
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • DNA, Ribosomal / chemistry
  • DNA, Ribosomal / genetics
  • Fatal Outcome
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Molecular Sequence Data
  • Mycobacterium avium Complex / classification
  • Mycobacterium avium Complex / drug effects
  • Mycobacterium avium Complex / genetics
  • Mycobacterium avium Complex / isolation & purification*
  • Phylogeny
  • RNA, Ribosomal, 16S / genetics
  • Radiography, Thoracic
  • Sequence Analysis, DNA
  • Tomography, X-Ray Computed
  • Tuberculosis, Pulmonary / diagnosis*
  • Tuberculosis, Pulmonary / diagnostic imaging
  • Tuberculosis, Pulmonary / microbiology*

Substances

  • Antitubercular Agents
  • DNA, Bacterial
  • DNA, Ribosomal
  • RNA, Ribosomal, 16S