Gadolinium-free MR in coarctation-can contrast-enhanced MR angiography be replaced?

Clin Imaging. 2016 May-Jun;40(3):414-8. doi: 10.1016/j.clinimag.2015.12.013. Epub 2016 Jan 15.

Abstract

Objective: To determine the difference in vessel measurements, signal-to-noise ratio (SNR), and voxel size between contrast-enhanced and noncontrast magnetic resonance techniques in patients with coarctation of the aorta (CoA).

Materials and methods: In 39 patients, vessel size, SNR, and voxel size were compared in cine magnetic resonance imaging (MRI), gadolinium-free magnetic resonance angiography (Gd-free MRA), and contrast-enhanced MRA (ce-MRA).

Results: There was no significant difference in measurement and SNR, but there was a significant difference in voxel size (P<.001).

Conclusions: Our results show that, in CoA patients, monitoring of vessel size using cine MRI and Gd-free MRA is equivalent to ce-MRA while being less invasive.

Keywords: Coarctation of the aorta; Gadolinium; MR angiography; Pediatric.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Aorta / abnormalities
  • Aorta / diagnostic imaging*
  • Aortic Coarctation / diagnostic imaging*
  • Contrast Media*
  • Female
  • Gadolinium DTPA
  • Gadolinium*
  • Humans
  • Image Enhancement / methods*
  • Magnetic Resonance Angiography / methods*
  • Magnetic Resonance Imaging, Cine / methods
  • Male
  • Signal-To-Noise Ratio
  • Young Adult

Substances

  • Contrast Media
  • Gadolinium
  • Gadolinium DTPA