Severe meningeal fibrinoid vasculitis associated with Theileria taurotragi infection in two short-horned Zebu cattle

Trop Anim Health Prod. 2016 Aug;48(6):1297-9. doi: 10.1007/s11250-016-1072-z. Epub 2016 May 4.

Abstract

The Authors describe a severe vasculitis with fibrinoid necrosis of the meningeal arteries observed in two brains of indigenous short-horn zebu (Bos indicus) cattle, with bovine cerebral theileriosis (BCT) caused by a tick-transmitted hemoprotozoan, Theileria taurotragi, from Northern Tanzania. In the Author's opinion, the role of T. taurotragi infection in the angiocentric and angiodestructive detected features remains to be evaluated. A possible immunopathologic cancerous mechanism, secondary to the lymphoid deregulation, could be involved. This report suggests further studies to better characterize the lymphoid cell involvement in the pathogenesis of the meningeal vascular lesions by T. taurotragi.

Keywords: Brain; East-African short-horned Zebu; Histopathology; Immunopathology Theileria.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Cattle
  • Diagnosis, Differential
  • Female
  • Tanzania
  • Theileria / isolation & purification*
  • Theileriasis / diagnosis*
  • Tick Infestations / diagnosis
  • Tick Infestations / veterinary
  • Vasculitis, Central Nervous System / diagnosis
  • Vasculitis, Central Nervous System / veterinary