Modulation of microglia polarization dynamics during diabetic retinopathy in db/db mice

Biochim Biophys Acta. 2016 Sep;1862(9):1663-74. doi: 10.1016/j.bbadis.2016.05.024. Epub 2016 Jun 4.
No abstract available

Keywords: Diabetic retinopathy; Inflammation; Microglia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antigens, Differentiation, B-Lymphocyte / genetics
  • Arginase / genetics
  • Cell Line
  • Cytokines / blood
  • Cytokines / genetics
  • Diabetic Retinopathy / etiology
  • Diabetic Retinopathy / pathology*
  • Diabetic Retinopathy / physiopathology*
  • Disease Models, Animal
  • Electroretinography
  • Endotoxins / blood
  • Gene Expression Profiling
  • Histocompatibility Antigens Class II / genetics
  • Humans
  • Inflammasomes / physiology
  • Inflammation Mediators / blood
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, Mutant Strains
  • Microglia / classification
  • Microglia / pathology*
  • Microglia / physiology*
  • Nitric Oxide Synthase Type II / genetics
  • RNA, Messenger / genetics
  • RNA, Messenger / metabolism
  • Receptors, Leptin / genetics
  • Retina / pathology
  • Retina / physiopathology

Substances

  • Antigens, Differentiation, B-Lymphocyte
  • Cytokines
  • Endotoxins
  • Histocompatibility Antigens Class II
  • Inflammasomes
  • Inflammation Mediators
  • RNA, Messenger
  • Receptors, Leptin
  • invariant chain
  • leptin receptor, mouse
  • NOS2 protein, human
  • Nitric Oxide Synthase Type II
  • Nos2 protein, mouse
  • ARG1 protein, human
  • Arg1 protein, mouse
  • Arginase