pDCs Take a Deep Breath to Fight Viruses

Luciana Berod; Tim Sparwasser

doi:10.1016/j.immuni.2016.06.005

pDCs Take a Deep Breath to Fight Viruses

Immunity. 2016 Jun 21;44(6):1246-8. doi: 10.1016/j.immuni.2016.06.005.

Authors

Luciana Berod¹, Tim Sparwasser²

Affiliations

¹ Institute of Infection Immunology, TWINCORE, Centre for Experimental and Clinical Infection Research; a joint venture between the Medical School Hannover (MHH) and the Helmholtz Centre for Infection Research (HZI), Feodor-Lynen-Strasse 7, 30625 Hannover, Germany. Electronic address: luciana.berod@twincore.de.
² Institute of Infection Immunology, TWINCORE, Centre for Experimental and Clinical Infection Research; a joint venture between the Medical School Hannover (MHH) and the Helmholtz Centre for Infection Research (HZI), Feodor-Lynen-Strasse 7, 30625 Hannover, Germany. Electronic address: sparwasser.tim@mh-hannover.de.

PMID: 27332726
DOI: 10.1016/j.immuni.2016.06.005

Abstract

Conventional dendritic cells (cDCs) and plasmacytoid dendritic cells (pDCs) serve non-overlapping functions in immune responses. In this issue of Immunity, Pearce and colleagues (2016) report that pDCs use different metabolic pathways from cDCs to support their specialized function.

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MeSH terms

Dendritic Cells / immunology*
Humans
Immunity*
Viruses