The importance of cytogenetic and molecular analyses in eosinophilia-associated myeloproliferative neoplasms: an unusual case with normal karyotype and TNIP1- PDGFRB rearrangement and overview of PDGFRB partner genes

Leuk Lymphoma. 2017 Feb;58(2):489-493. doi: 10.1080/10428194.2016.1197396. Epub 2016 Jun 24.

Authors

M Maccaferri¹, V Pierini², D Di Giacomo², P Zucchini¹, F Forghieri¹, G Bonacorsi¹, A Paolini¹, C Quadrelli¹, F Giacobbi¹, F Fontana³, G Cappelli³, L Potenza¹, R Marasca¹, M Luppi¹, C Mecucci²

Affiliations

¹ a Department of Medical and Surgical Sciences Maternal-Infantile and of the Adult, Section of Hematology , University of Modena and Reggio Emilia , Modena , Italy.
² b Department of Medicine, Laboratory of Cytogenetics and Molecular Genetics , University of Perugia , Perugia , Italy.
³ c Surgical, Medical and Dental Department of Morphological Sciences Related to Transplant, Oncology and Regenerative Medicine, Section of Nephrology , University of Modena and Reggio Emilia , Modena , Italy.

PMID: 27337990
DOI: 10.1080/10428194.2016.1197396

No abstract available

Publication types

Case Reports
Letter
Review

MeSH terms

Adult
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Biopsy
Bone Marrow / pathology
DNA Mutational Analysis
DNA-Binding Proteins / genetics*
Humans
Karyotype*
Leukocyte Count
Male
Myeloproliferative Disorders / diagnosis*
Myeloproliferative Disorders / drug therapy
Myeloproliferative Disorders / genetics*
Oncogene Proteins, Fusion / genetics*
Receptor, Platelet-Derived Growth Factor beta / genetics*
Ultrasonography

Substances

DNA-Binding Proteins
Oncogene Proteins, Fusion
TNIP1 protein, human
PDGFRB protein, human
Receptor, Platelet-Derived Growth Factor beta