[Correlation between MALDI-TOF Vitek-MSTM system and conventional identification methods of gastrointestinal infection causing bacteria]

Rev Esp Quimioter. 2016 Oct;29(5):265-8. Epub 2016 Jul 22.
[Article in Spanish]

Abstract

Objective: Rapid identification of pathogens is essential for the diagnosis of gastrointestinal infections. Matrix-assisted laser desorption/ionization time of flight (MALDI-TOF) mass spectrometry has shown to be effective and fast for the identification of microorganisms. The objective of this study was to evaluate the correlation between Vitek-MSTM and conventional methods for bacterial identification causing gastrointestinal infection.

Methods: A total of 329 gastrointestinal pathogens were identified using Vitek-MSTM (v2 SARAMIS MS -ID, bioMérieux, Marcy-I´Étoile, France) and routine diagnostic methods simultaneously. In cases of discrepancy 16SrRNA gene sequencing was performed.

Results: The correlation between Vitek-MSTM and diagnostic methods was 100% except for Yersinia enterocolitica (94.1%), Helicobacter pylori (10%) and Aeromonas veronii (0 %).

Conclusions: Vitek-MSTM is a quick and useful method for identification of enterophatogenic bacteria. It is necessary to improve the performance of the system for the identification of H. pylori and A. veronii.

MeSH terms

  • Bacteria / chemistry*
  • Bacteria / genetics
  • Gastrointestinal Diseases / microbiology*
  • Genotype
  • Humans
  • Infections / microbiology*
  • RNA, Bacterial / analysis
  • RNA, Ribosomal, 16S / analysis
  • Reproducibility of Results
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods*

Substances

  • RNA, Bacterial
  • RNA, Ribosomal, 16S