Transperineal Prostate Core Needle Biopsy: A Comparison of Coaxial Versus Noncoaxial Method in a Randomised Trial

Cardiovasc Intervent Radiol. 2016 Dec;39(12):1736-1742. doi: 10.1007/s00270-016-1437-8. Epub 2016 Aug 2.

Abstract

Purpose: To compare the procedural time and complication rate of coaxial technique with those of noncoaxial technique in transperineal prostate biopsy.

Materials and methods: Transperineal prostate biopsy with coaxial (first group, n = 120) and noncoaxial (second group, n = 120) methods was performed randomly in 240 patients. The procedural time was recorded. The level of pain experienced during the procedure was assessed on a visual analogue scale (VAS), and the rate of complications was evaluated in comparison of the two methods.

Results: The procedural time was significantly shorter in the first group (p < 0.001). In the first group, pain occurred less frequently (p = 0.002), with a significantly lower VAS score being experienced (p < 0.002). No patient had post procedural fever. Haematuria (p = 0.029) and haemorrhage from the site of biopsy (p < 0.001) were seen less frequently in the first group. There was no significant difference in the rate of urethral haemorrhage between the two groups (p = 0.059). Urinary retention occurred less commonly in the first group (p = 0.029). No significant difference was seen in the rate of dysuria between the two groups (p = 0.078).

Conclusions: Transperineal prostate biopsy using a coaxial needle is a faster and less painful method with a lower rate of complications compared with conventional noncoaxial technique.

Keywords: Coaxial; Complication; Image-guided biopsy; Prostate; Transperineal.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Aged, 80 and over
  • Biopsy, Large-Core Needle / adverse effects
  • Biopsy, Large-Core Needle / methods
  • Hematuria / etiology
  • Humans
  • Male
  • Middle Aged
  • Pain / etiology*
  • Prospective Studies
  • Prostate / pathology*
  • Prostatic Neoplasms / pathology*
  • Time Factors
  • Urinary Retention / etiology