Assessment of drug administration via feeding tube and the knowledge of health-care professionals in a university hospital

Eur J Clin Nutr. 2017 Feb;71(2):164-168. doi: 10.1038/ejcn.2016.147. Epub 2016 Aug 10.

Abstract

Background/objectives: The use of drugs via feeding tube is problematic. Appropriate techniques must be used during the administration to prevent obstruction of a feeding tube, to avoid inadequate drug effects and to minimize the risk of toxicity of the given pharmaceuticals.

Subjects/methods: In this study, medications of all the patients in a University Hospital with 1100 beds were monitored to identify the appropriateness of administration. The study was performed on 5 days each in 5 consecutive weeks to observe the current practice. After evaluation of practice, a questionnaire was given to doctors, nurses and pharmacists to determine the health-care professionals' attitudes on drug administration through a feeding tube.

Results: A total of 225 drugs (out of 13 935) were administered via feeding tube during the study period and 40.5% (n=91) were not administered in appropriate dosage forms. Only 86% of the doctors and 98% of the nurses stated that they pay attention to the suitability of drugs when they prescribe or administer drugs via feeding tube. Only 58% of pharmacists, 17% of nurses and 24% of doctors were aware of the fact that enteric-coated tablets should not be crushed owing to the risk of tube occlusion and lack of efficacy when they are administered via feeding tube.

Conclusions: This study demonstrated the discordance between the theoretical knowledge and the practical performance of the health-care professionals in drug administration. In patients with feeding tubes, assessment of drug dosage forms by a pharmacist would be beneficial for appropriate administration and to prevent drug interactions.

MeSH terms

  • Adult
  • Dosage Forms
  • Drug Administration Routes*
  • Enteral Nutrition / methods*
  • Female
  • Health Knowledge, Attitudes, Practice*
  • Health Personnel / psychology*
  • Hospitals, University
  • Humans
  • Male
  • Middle Aged
  • Process Assessment, Health Care

Substances

  • Dosage Forms