Predictors of recurrence after stent-assisted coil embolization of paraclinoid aneurysms

J Clin Neurosci. 2016 Nov:33:173-176. doi: 10.1016/j.jocn.2016.03.039. Epub 2016 Aug 27.

Abstract

Stent-assisted coil embolization has been increasingly used to treat paraclinoid aneurysms. The study was aimed to evaluate safety and efficacy of stent-assisted coil embolization for paraclinoid aneurysms and explore the factors influencing the long-term outcomes. Under an institutional review board approved protocol, the clinical and angiographic data of 129 paraclinoid aneurysms in 120 patients (Male:Female=36:84; median age, 52years; range, 21-84) treated by stent-assisted coil embolization were reviewed retrospectively. Clinical status, aneurysmal morphology, treatment strategy and results were analyzed using Chi-squared tests in the univariate analysis and further analyzed using backward stepwise logistic regression. The univariate analysis indicated significance between the groups regarding hypertension, ruptured aneurysms, size, wide neck and immediate treatment results (P<0.05). Multivariate logistic regression analysis found that ruptured aneurysms (odds ratio [OR]=5.893, 95% confidence interval [CI], 1.512-23.054; p=0.011), larger size (OR=2.339; 95%CI, 1.148-4.781; p=0.020) and hypertension (OR=6.143; 95%CI, 1.560-24.183; p=0.009) might be predictors of recurrence. Stent-assisted coil embolization of paraclinoid aneurysm has a risk of recurrence. Ruptured aneurysms, larger size and hypertension may be the risk factors for recurrence.

Keywords: Endovascular treatment; Intracranial aneurysm; Paraclinoid aneurysm; Recurrence; Stent-assisted coil embolization.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aneurysm, Ruptured / diagnostic imaging
  • Aneurysm, Ruptured / therapy*
  • Blood Vessel Prosthesis
  • Cerebral Angiography / methods
  • Embolization, Therapeutic / instrumentation
  • Embolization, Therapeutic / trends*
  • Female
  • Follow-Up Studies
  • Humans
  • Intracranial Aneurysm / diagnostic imaging
  • Intracranial Aneurysm / therapy*
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Recurrence
  • Retrospective Studies
  • Stents*
  • Treatment Outcome
  • Young Adult