Streptococcus suis Serotype 2 Capsule In Vivo

Emerg Infect Dis. 2016 Oct;22(10):1793-6. doi: 10.3201/eid2210.151640.

Abstract

Many Streptococcus suis isolates from porcine endocarditis in slaughterhouses have lost their capsule and are considered avirulent. However, we retrieved capsule- and virulence-recovered S. suis after in vivo passages of a nonencapsulated strain in mice, suggesting that nonencapsulated S. suis are still potentially hazardous for persons in the swine industry.

Keywords: Streptococcus suis; bacteria; bacterial capsule; mutation; occupational health; pigs; porcine endocarditis; swine; zoonoses; zoonosis.

MeSH terms

  • Animals
  • Bacterial Capsules / genetics*
  • Bacterial Capsules / physiology
  • Endocarditis, Bacterial / microbiology
  • Endocarditis, Bacterial / veterinary
  • Genes, Bacterial
  • Mice
  • Mice, Inbred C57BL
  • Multigene Family
  • Mutation
  • Polysaccharides, Bacterial / genetics
  • Serial Passage
  • Serotyping
  • Streptococcal Infections / microbiology
  • Streptococcal Infections / veterinary
  • Streptococcus suis / classification
  • Streptococcus suis / genetics
  • Streptococcus suis / isolation & purification
  • Streptococcus suis / pathogenicity*
  • Swine
  • Swine Diseases / microbiology
  • Virulence / genetics
  • Virulence Factors / genetics*

Substances

  • Polysaccharides, Bacterial
  • Virulence Factors