Nonalcoholic fatty liver disease, association with cardiovascular disease and treatment. (I). Nonalcoholic fatty liver disease and its association with cardiovascular disease
Clin Investig Arterioscler. 2017 May-Jun;29(3):141-148.
doi: 10.1016/j.arteri.2016.06.003.
Epub 2016 Sep 28.
[Article in
English,
Spanish]
Affiliations
- 1 Unidad de Lípidos, Servicio de Medicina Interna, Hospital San Pedro, Logroño, España. Electronic address: abrea@riojasalud.es.
- 2 Unidad de Lípidos y Riesgo Vascular, Servicio de Medicina Interna, Hospital Universitario de Bellvitge, Idibell. CiberObn, L'Hospitalet de Llobregat, Barcelona, España.
- 3 Servicio de Endocrinología, Hospital Clínico , Valencia, España.
- 4 Atención Primaria, Área Sanitaria de Delicias, Zaragoza, España.
- 5 Centro de Salud de Bembibre, Bembibre, León, España.
- 6 Departamento de Medicina, Universidad de Málaga.
- 7 Servicio de Endocrinología, Hospital Universitario Dr. Peset, Universitat de València , Valencia, España.
- 8 Atención Primaria, Centro de Salud de Prosperidad, Madrid, España.
- 9 Unidad de Lípidos, Servicio de Medicina Interna, Hospital General Universitario Gregorio Marañón, Universidad Complutense , Madrid, España.
- 10 Unidad de Lípidos y Riesgo Vascular, Servicio de Endocrinología y Nutrición, Hospital del Mar, Universitat Autònoma de Barcelona , Barcelona, España.
Abstract
Non-alcoholic fatty liver disease (NAFLD) comprises a series of histologically lesions similar to those induced by alcohol consumption in people with very little or no liver damage. The importance of NAFLD is its high prevalence in the Western world and, from the point of view of the liver, in its gradual progression from steatosis to steatohepatitis, cirrhosis, and liver cancer. During the last decade it has been observed that NAFLD leads to an increased cardiovascular risk with acceleration of arteriosclerosis and events related to it, being the main cause of its morbidity and mortality. This review, updated to January 2016, consists of two parts, with the first part analysing the association of NAFLD with cardiovascular disease.
Keywords:
Arteriosclerosis; Atherosclerosis; Cardiovascular diseases; Cardiovascular risk; Enfermedad del hígado graso no alcohólica; Enfermedades cardiovasculares; Esteatohepatitis no alcohólica; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Riesgo cardiovascular; Tratamiento; Treatment.
Copyright © 2016 Sociedad Española de Arteriosclerosis. Publicado por Elsevier España, S.L.U. All rights reserved.
MeSH terms
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Atherosclerosis / etiology*
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Atherosclerosis / mortality
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Cardiovascular Diseases / etiology*
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Cardiovascular Diseases / mortality
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Disease Progression
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Humans
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Non-alcoholic Fatty Liver Disease / complications*
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Non-alcoholic Fatty Liver Disease / mortality
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Non-alcoholic Fatty Liver Disease / physiopathology
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Risk Factors