β-Catenin Mutations: Insights into the APC Pathway and the Power of Genetics

Cancer Res. 2016 Oct 1;76(19):5587-5589. doi: 10.1158/0008-5472.CAN-16-2387.

Authors

Patrice J Morin¹, Kenneth W Kinzler², Andrew B Sparks³

Affiliations

¹ Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania. patmorin@exchange.upenn.edu.
² Ludwig Center at Johns Hopkins University and The Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland.
³ Roche Molecular Solutions, Pleasanton, California.

PMID: 27698186
DOI: 10.1158/0008-5472.CAN-16-2387

No abstract available

MeSH terms

Adenomatous Polyposis Coli Protein / genetics
Adenomatous Polyposis Coli Protein / metabolism
Genes, APC*
Humans
Mutation*
Neoplasms / genetics*
Neoplasms / metabolism
beta Catenin / genetics*
beta Catenin / metabolism

Substances

APC protein, human
Adenomatous Polyposis Coli Protein
CTNNB1 protein, human
beta Catenin