Iron-Catalyzed Synthesis of Sulfur-Containing Heterocycles

J Org Chem. 2017 Apr 21;82(8):4020-4036. doi: 10.1021/acs.joc.6b01827. Epub 2016 Oct 13.

Abstract

An iron-catalyzed synthesis of sulfur- and sulfone-containing heterocycles is reported. The method is based on the cyclization of readily available substrates and proceeded with high efficiency and diastereoselectivity. A variety of sulfur-containing heterocycles bearing moieties suitable for subsequent functionalization are prepared. Illustrative examples of such postcyclization modifications are also presented.

Publication types

  • Research Support, Non-U.S. Gov't