Maternal abuse history and reduced fetal heart rate variability: Abuse-related sleep disturbance is a mediator

Dev Psychopathol. 2017 Aug;29(3):1023-1034. doi: 10.1017/S0954579416000997. Epub 2016 Oct 20.

Abstract

The consequences of childhood maltreatment are profound and long lasting. Not only does the victim of abuse suffer as a child, but there is mounting evidence that a history of maltreatment places the next generation at risk for significant psychopathology. Research identifies postnatal factors as affecting this intergenerational transmission of trauma. However, emerging evidence suggests that part of this risk may be transmitted before birth, passed on via abuse-related alterations in the in utero environment that are as yet largely unidentified. To date, no study has directly assessed the influence of pregnant women's abuse history on fetal neurobehavioral development, nor considered trauma-associated poor sleep quality as a mediator reflecting established physiological dysregulation. Using data from 262 pregnant adolescents (ages 14-19), a population at elevated risk for childhood maltreatment, the current study examined maternal emotional abuse history and sleep quality in relation to third-trimester fetal resting heart rate variability, an index of parasympathetic nervous system functioning. The results indicate that maternal emotional abuse history is indirectly associated with lower fetal heart rate variability via abuse-related sleep disturbances. These data demonstrate an association between maternal abuse histories and fetal development, showing that at least part of the intergenerational transmission of risk occurs during pregnancy.

MeSH terms

  • Adolescent
  • Adult
  • Adult Survivors of Child Abuse*
  • Child Abuse*
  • Female
  • Fetal Development / physiology*
  • Heart Rate, Fetal / physiology*
  • Humans
  • Pregnancy
  • Pregnancy Complications / physiopathology*
  • Pregnancy in Adolescence / physiology*
  • Risk Factors
  • Sleep Wake Disorders / physiopathology*
  • Young Adult